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DEXMEDETOMIDINE PREVENTS PDIA3 DECREASE BY ACTIVATING α2-ADRENERGIC RECEPTOR TO ALLEVIATE INTESTINAL I/R IN MICE

Background: Dexmedetomidine (DEX) attenuates intestinal I/R injury, but its mechanism of action remains to be further elucidated. Protein disulfide isomerase A3 (PDIA3) has been reported as a therapeutic protein for the prevention and treatment of intestinal I/R injury. This study was to investigate...

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Detalles Bibliográficos
Autores principales: Zhan, YaQing, Chen, ZhaoRong, Qiu, YuXin, Deng, Qiwen, Huang, WenQi, Wen, ShiHong, Shen, JianTong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803385/
https://www.ncbi.nlm.nih.gov/pubmed/36374735
http://dx.doi.org/10.1097/SHK.0000000000002011