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Development of a rapid image-based high-content imaging screening assay to evaluate therapeutic antibodies against the monkeypox virus

Antibody-based therapy is emerging as a critical therapeutic countermeasure to treat acute viral infections by offering rapid protection against clinical disease. The advancements in structural biology made it feasible to rationalize monoclonal antibodies (mAbs) by identifying key and, possibly, neu...

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Detalles Bibliográficos
Autores principales: Kota, Krishna P., Ziółkowska, Natasza E., Wei, Jiayi, Peng, Junzhong, Ordonez, David, Raney, Christy, Prigge, Jon, Hooper, Jay W., Awasthi, Mayanka, Goebel, Scott J., Zabel, Brian A., Nasar, Farooq, Lederman, Seth, Bavari, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803393/
https://www.ncbi.nlm.nih.gov/pubmed/36592670
http://dx.doi.org/10.1016/j.antiviral.2022.105513