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Development of a rapid image-based high-content imaging screening assay to evaluate therapeutic antibodies against the monkeypox virus
Antibody-based therapy is emerging as a critical therapeutic countermeasure to treat acute viral infections by offering rapid protection against clinical disease. The advancements in structural biology made it feasible to rationalize monoclonal antibodies (mAbs) by identifying key and, possibly, neu...
Autores principales: | Kota, Krishna P., Ziółkowska, Natasza E., Wei, Jiayi, Peng, Junzhong, Ordonez, David, Raney, Christy, Prigge, Jon, Hooper, Jay W., Awasthi, Mayanka, Goebel, Scott J., Zabel, Brian A., Nasar, Farooq, Lederman, Seth, Bavari, Sina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803393/ https://www.ncbi.nlm.nih.gov/pubmed/36592670 http://dx.doi.org/10.1016/j.antiviral.2022.105513 |
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