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Inhibition of PFKFB Preserves Intestinal Barrier Function in Sepsis by Inhibiting NLRP3/GSDMD

Intestinal barrier dysfunction is associated with the occurrence and development of sepsis. Further, aerobic glycolysis plays an essential role in inflammation and cell death. This study is aimed at investigating the protective effect and mechanism of PFKFB3 inhibition on intestinal barrier dysfunct...

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Detalles Bibliográficos
Autores principales: Zhang, Yongsheng, Liu, Yukun, Xie, Zhenxing, Liu, Qinxin, Zhuang, Yangfan, Xie, Weiming, Wang, Xiang, Gao, Wei, Yang, Fan, Li, Zhanfei, Bai, Xiangjun, Wang, Yuchang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803577/
https://www.ncbi.nlm.nih.gov/pubmed/36589684
http://dx.doi.org/10.1155/2022/8704016