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Effects of acute estradiol and progesterone on perimenstrual exacerbation of suicidal ideation and related symptoms: a crossover randomized controlled trial

Female suicide attempts peak peri-menstrually—around the onset of menses—when the ovarian steroids estradiol (E2) and progesterone (P4) fall rapidly. Given preclinical evidence that withdrawal from either E2 or P4 can provoke behaviors consistent with elevated suicide risk, we hypothesized that with...

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Detalles Bibliográficos
Autores principales: Eisenlohr-Moul, Tory A., Bowers, Savannah M., Prinstein, Mitchell J., Schmalenberger, Katja M., Walsh, Erin C., Young, Steven L., Rubinow, David R., Girdler, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803670/
https://www.ncbi.nlm.nih.gov/pubmed/36585408
http://dx.doi.org/10.1038/s41398-022-02294-1