MiR-150 blunts cardiac dysfunction in mice with cardiomyocyte loss of β(1)-adrenergic receptor/β-arrestin signaling and controls a unique transcriptome

The β(1)-adrenergic receptor (β(1)AR) is found primarily in hearts (mainly in cardiomyocytes [CMs]) and β-arrestin-mediated β(1)AR signaling elicits cardioprotection through CM survival. We showed that microRNA-150 (miR-150) is upregulated by β-arrestin-mediated β(1)AR signaling and that CM miR-150...

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Detalles Bibliográficos
Autores principales: Moukette, Bruno, Kawaguchi, Satoshi, Sepulveda, Marisa N., Hayasaka, Taiki, Aonuma, Tatsuya, Liangpunsakul, Suthat, Yang, Lei, Dharmakumar, Rohan, Conway, Simon J., Kim, Il-man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803679/
https://www.ncbi.nlm.nih.gov/pubmed/36585403
http://dx.doi.org/10.1038/s41420-022-01295-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803679/
https://www.ncbi.nlm.nih.gov/pubmed/36585403
http://dx.doi.org/10.1038/s41420-022-01295-9

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