scAVENGERS: a genotype-based deconvolution of individuals in multiplexed single-cell ATAC-seq data without reference genotypes

Genetic differences inferred from sequencing reads can be used for demultiplexing of pooled single-cell RNA-seq (scRNA-seq) data across multiple donors without WGS-based reference genotypes. However, such methods could not be directly applied to single-cell ATAC-seq (scATAC-seq) data owing to the lo...

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Detalles Bibliográficos
Autores principales: Han, Seungbeom, Kim, Kyukwang, Park, Seongwan, Lee, Andrew J, Chun, Hyonho, Jung, Inkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
High Throughput Sequencing Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803874/
https://www.ncbi.nlm.nih.gov/pubmed/36601579
http://dx.doi.org/10.1093/nargab/lqac095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803874/
https://www.ncbi.nlm.nih.gov/pubmed/36601579
http://dx.doi.org/10.1093/nargab/lqac095

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