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Selective somatostatin receptor 5 inhibition improves hepatic insulin sensitivity

Diabetes is a metabolic disorder with an increasing global prevalence. Somatostatin (SST), a peptide hormone, regulates hormone secretion via five SST receptor (SSTR) subtypes (SSTR1–5) in a tissue‐specific manner. As SSTR5 is expressed in pancreatic β‐cells and intestinal L‐cells, studies have sugg...

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Detalles Bibliográficos
Autores principales: Tamura, Yumiko Okano, Sugama, Jun, Abe, Shin‐ichi, Shimizu, Yuji, Hirose, Hideki, Watanabe, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803904/
https://www.ncbi.nlm.nih.gov/pubmed/36585794
http://dx.doi.org/10.1002/prp2.1043