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Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era
pLGGs are a group of tumors for which the era of molecular diagnostics has truly shifted treatment paradigms and patient care. The discovery that this group of tumors is driven by single-gene alterations/fusions in the MAPK pathway has resulted in relatively rapid translation into targeted therapy o...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803951/ https://www.ncbi.nlm.nih.gov/pubmed/36566593 http://dx.doi.org/10.1016/j.neo.2022.100857 |