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Pediatric low-grade glioma: Targeted therapeutics and clinical trials in the molecular era

pLGGs are a group of tumors for which the era of molecular diagnostics has truly shifted treatment paradigms and patient care. The discovery that this group of tumors is driven by single-gene alterations/fusions in the MAPK pathway has resulted in relatively rapid translation into targeted therapy o...

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Detalles Bibliográficos
Autores principales: Manoharan, Neevika, Liu, Kevin X., Mueller, Sabine, Haas-Kogan, Daphne A., Bandopadhayay, Pratiti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9803951/
https://www.ncbi.nlm.nih.gov/pubmed/36566593
http://dx.doi.org/10.1016/j.neo.2022.100857

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