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Transducin-Deficient Rod Photoreceptors Evaluated With Optical Coherence Tomography and Oxygen Consumption Rate Energy Biomarkers

PURPOSE: To test the hypothesis that rod energy biomarkers in light and dark are similar in mice without functional rod transducin (Gnat1(rd17)). METHODS: Gnat1(rd17) and wildtype (WT) mice were studied in canonically low energy demand (light) and high energy demand (dark) conditions. We measured ro...

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Detalles Bibliográficos
Autores principales: Berkowitz, Bruce A., Podolsky, Robert H., Childers, Karen Lins, Roberts, Robin, Katz, Ryan, Waseem, Rida, Robbings, Brian M., Hass, Daniel T., Hurley, James B., Sweet, Ian R., Goodman, Cole, Qian, Haohua, Alvisio, Bruno, Heaps, Sam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804021/
https://www.ncbi.nlm.nih.gov/pubmed/36576748
http://dx.doi.org/10.1167/iovs.63.13.22