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MicroRNA‐140‐5p inhibitor attenuates memory impairment induced by amyloid‐ß oligomer in vivo possibly through Pin1 regulation

AIMS: The peptidyl‐prolyl cis/trans isomerase, Pin1, has a protective role in age‐related neurodegeneration by targeting different phosphorylation sites of tau and the key proteins required to produce Amyloid‐β, which are the well‐known molecular signatures of Alzheimer's disease (AD) neuropath...

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Detalles Bibliográficos
Autores principales: Khodabakhsh, Pariya, Bazrgar, Maryam, Mohagheghi, Fatemeh, Parvardeh, Siavash, Ahmadiani, Abolhassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804077/
https://www.ncbi.nlm.nih.gov/pubmed/36184817
http://dx.doi.org/10.1111/cns.13980