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The regulatory mechanism and therapeutic potential of transcription factor EB in neurodegenerative diseases

The autophagy‐lysosomal pathway (ALP) is involved in the degradation of protein aggregates and damaged organelles. Transcription factor EB (TFEB), a major regulator of ALP, has emerged as a leading factor in addressing neurodegenerative disease pathology, including Alzheimer's disease (AD), Par...

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Detalles Bibliográficos
Autores principales: Jiao, Fengjuan, Zhou, Bojie, Meng, Lingyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804079/
https://www.ncbi.nlm.nih.gov/pubmed/36184826
http://dx.doi.org/10.1111/cns.13985