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Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice
Multiple genome-wide association studies (GWAS) have identified specific genetic variants in the coiled-coil domain containing 92 (CCDC92) locus that is associated with obesity and type 2 diabetes in humans. However, the biological function of CCDC92 in obesity and insulin resistance remains to be e...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804112/ https://www.ncbi.nlm.nih.gov/pubmed/36594018 http://dx.doi.org/10.1016/j.isci.2022.105769 |