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Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice

Multiple genome-wide association studies (GWAS) have identified specific genetic variants in the coiled-coil domain containing 92 (CCDC92) locus that is associated with obesity and type 2 diabetes in humans. However, the biological function of CCDC92 in obesity and insulin resistance remains to be e...

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Detalles Bibliográficos
Autores principales: Ren, Lu, Du, Wa, Song, Dan, Lu, Haocheng, Hamblin, Milton H., Wang, Chenran, Du, Chunying, Fan, Guo-Chang, Becker, Richard C., Fan, Yanbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804112/
https://www.ncbi.nlm.nih.gov/pubmed/36594018
http://dx.doi.org/10.1016/j.isci.2022.105769