Evidence of shared transcriptomic dysregulation of HNRNPU-related disorder between human organoids and embryonic mice

Generating effective therapies for neurodevelopmental disorders has remained elusive. An emerging drug discovery approach for neurodevelopmental disorders is to characterize transcriptome-wide dysregulation in an appropriate model system and screen therapeutics based on their capacity to restore fun...

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Detalles Bibliográficos
Autores principales: Ressler, Andrew K., Sampaio, Gabriela L.A., Dugger, Sarah A., Sapir, Tamar, Krizay, Daniel, Boland, Michael J., Reiner, Orly, Goldstein, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804147/
https://www.ncbi.nlm.nih.gov/pubmed/36594023
http://dx.doi.org/10.1016/j.isci.2022.105797

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804147/
https://www.ncbi.nlm.nih.gov/pubmed/36594023
http://dx.doi.org/10.1016/j.isci.2022.105797

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