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Evidence of shared transcriptomic dysregulation of HNRNPU-related disorder between human organoids and embryonic mice
Generating effective therapies for neurodevelopmental disorders has remained elusive. An emerging drug discovery approach for neurodevelopmental disorders is to characterize transcriptome-wide dysregulation in an appropriate model system and screen therapeutics based on their capacity to restore fun...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804147/ https://www.ncbi.nlm.nih.gov/pubmed/36594023 http://dx.doi.org/10.1016/j.isci.2022.105797 |