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Gaining Insights on the Interactions of a Class of Decorated (2‐([2,2′‐Bipyridin]‐6‐yl)phenyl)platinum Compounds with c‐Myc Oncogene Promoter G‐Quadruplex and Other DNA Structures

Organometallic molecules offer some of the most promising scaffolds for interaction with G‐quadruplex nucleic acids. We report the efficient synthesis of a family of organoplatinum(II) complexes, featuring a 2‐([2,2′‐bipyridin]‐6‐yl)phenyl tridentate (N(∧)N(∧)C) ligand, that incorporates peripheral...

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Detalles Bibliográficos
Autores principales: Savva, Loukiani, Fossépré, Mathieu, Keramidas, Odysseas, Themistokleous, Alexandros, Rizeq, Natalia, Panagiotou, Nikos, Leclercq, Maxime, Nicolaidou, Eliana, Surin, Mathieu, Hayes, Sophia C., Georgiades, Savvas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804160/
https://www.ncbi.nlm.nih.gov/pubmed/35726630
http://dx.doi.org/10.1002/chem.202201497