Tetrazine‐Triggered Bioorthogonal Cleavage of trans‐Cyclooctene‐Caged Phenols Using a Minimal Self‐Immolative Linker Strategy

Bond‐cleavage reactions triggered by bioorthogonal tetrazine ligation have emerged as strategies to chemically control the function of (bio)molecules and achieve activation of prodrugs in living systems. While most of these approaches make use of caged amines, current methods for the release of phen...

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Detalles Bibliográficos
Autores principales: Keppel, Patrick, Sohr, Barbara, Kuba, Walter, Goldeck, Marion, Skrinjar, Philipp, Carlson, Jonathan C. T., Mikula, Hannes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804162/
https://www.ncbi.nlm.nih.gov/pubmed/35921044
http://dx.doi.org/10.1002/cbic.202200363

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804162/
https://www.ncbi.nlm.nih.gov/pubmed/35921044
http://dx.doi.org/10.1002/cbic.202200363

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