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Prostate cancer cells demonstrate unique metabolism and substrate adaptability acutely after androgen deprivation therapy

BACKGROUND: Androgen deprivation therapy (ADT) has been the standard of care for advanced hormone‐sensitive prostate cancer (PC), yet tumors invariably develop resistance resulting in castrate‐resistant PC. The acute response of cancer cells to ADT includes apoptosis and cell death, but a large frac...

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Detalles Bibliográficos
Autores principales: Filon, Mikolaj J., Gillette, Amani A., Yang, Bing, Khemees, Tariq A., Skala, Melissa C., Jarrard, David F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804183/
https://www.ncbi.nlm.nih.gov/pubmed/35980831
http://dx.doi.org/10.1002/pros.24428