G‐Quadruplex Recognition by DARPIns through Epitope/Paratope Analogy

We investigated the mechanisms leading to the specific recognition of Guanine Guadruplex (G4) by DARPins peptides, which can lead to the design of G4 s specific sensors. To this end we carried out all‐atom molecular dynamic simulations to unravel the interactions between specific nucleic acids, incl...

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Detalles Bibliográficos
Autores principales: Miclot, Tom, Bignon, Emmanuelle, Terenzi, Alessio, Grandemange, Stéphanie, Barone, Giampaolo, Monari, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804223/
https://www.ncbi.nlm.nih.gov/pubmed/35791808
http://dx.doi.org/10.1002/chem.202201824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804223/
https://www.ncbi.nlm.nih.gov/pubmed/35791808
http://dx.doi.org/10.1002/chem.202201824

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