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Fluorescence intensity and lifetime imaging of lipofuscin-like autofluorescence for label-free predicting clinical drug response in cancer

Conventional techniques for in vitro cancer drug screening require labor-intensive formalin fixation, paraffin embedding, and dye staining of tumor tissues at fixed endpoints. This way of assessment discards the valuable pharmacodynamic information in live cells over time. Here, we found endogenous...

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Detalles Bibliográficos
Autores principales: Yan, Yinghan, Xing, Fuqiang, Cao, Jiayue, Hu, Yiling, Li, Ling, Gao, Zhengyin, Jia, Hao, Miao, Kai, Shao, Fangyuan, Deng, Chu-Xia, Luo, Kathy Qian, Lee, Leo Tsz on, Liu, Tzu-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804248/
https://www.ncbi.nlm.nih.gov/pubmed/36566738
http://dx.doi.org/10.1016/j.redox.2022.102578