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Fluorescence intensity and lifetime imaging of lipofuscin-like autofluorescence for label-free predicting clinical drug response in cancer
Conventional techniques for in vitro cancer drug screening require labor-intensive formalin fixation, paraffin embedding, and dye staining of tumor tissues at fixed endpoints. This way of assessment discards the valuable pharmacodynamic information in live cells over time. Here, we found endogenous...
Autores principales: | Yan, Yinghan, Xing, Fuqiang, Cao, Jiayue, Hu, Yiling, Li, Ling, Gao, Zhengyin, Jia, Hao, Miao, Kai, Shao, Fangyuan, Deng, Chu-Xia, Luo, Kathy Qian, Lee, Leo Tsz on, Liu, Tzu-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804248/ https://www.ncbi.nlm.nih.gov/pubmed/36566738 http://dx.doi.org/10.1016/j.redox.2022.102578 |
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