Spin‐Labeled Riboswitch Synthesized from a Protected TPA Phosphoramidite Building Block

The nitroxide TPA (2,2,5,5‐tetramethyl‐pyrrolin‐1‐oxyl‐3‐acetylene) is an excellent spin label for EPR studies of RNA. Previous synthetic methods, however, are complicated and require special equipment. Herein, we describe a uridine derived phosphoramidite with a photocaged TPA unit attached. The li...

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Detalles Bibliográficos
Autores principales: Kaiser, Frank, Endeward, Burkhard, Collauto, Alberto, Scheffer, Ute, Prisner, Thomas F., Göbel, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804336/
https://www.ncbi.nlm.nih.gov/pubmed/35903916
http://dx.doi.org/10.1002/chem.202201822

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804336/
https://www.ncbi.nlm.nih.gov/pubmed/35903916
http://dx.doi.org/10.1002/chem.202201822

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