Anti‐GPVI nanobody blocks collagen‐ and atherosclerotic plaque–induced GPVI clustering, signaling, and thrombus formation

BACKGROUND: The collagen receptor glycoprotein VI (GPVI) is an attractive antiplatelet target due to its critical role in thrombosis but minor involvement in hemostasis. OBJECTIVE: To investigate GPVI receptor involvement in platelet activation by collagen‐I and atherosclerotic plaque using novel bl...

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Detalles Bibliográficos
Autores principales: Jooss, Natalie J., Smith, Christopher W., Slater, Alexandre, Montague, Samantha J., Di, Ying, O'Shea, Christopher, Thomas, Mark R., Henskens, Yvonne M. C., Heemskerk, Johan W. M., Watson, Steve P., Poulter, Natalie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
PLATELETS
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804350/
https://www.ncbi.nlm.nih.gov/pubmed/35894121
http://dx.doi.org/10.1111/jth.15836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804350/
https://www.ncbi.nlm.nih.gov/pubmed/35894121
http://dx.doi.org/10.1111/jth.15836

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