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Calcium inhibits penetration of Alzheimer's Aβ(1)–(42) monomers into the membrane

Calcium ion regulation plays a crucial role in maintaining neuronal functions such as neurotransmitter release and synaptic plasticity. Copper (Cu(2+)) coordination to amyloid‐β (Aβ) has accelerated Aβ(1–42) aggregation that can trigger calcium dysregulation by enhancing the influx of calcium ions b...

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Detalles Bibliográficos
Autores principales: Boopathi, Subramanian, Garduño‐Juárez, Ramón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804374/
https://www.ncbi.nlm.nih.gov/pubmed/36321654
http://dx.doi.org/10.1002/prot.26403