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Multistep Continuous Flow Synthesis of Isolable NH(2)‐Sulfinamidines via Nucleophilic Addition to Transient Sulfurdiimide

The growing interest in novel sulfur pharmacophores led to recent advances in the synthesis of some S(IV) and S(VI) motifs. However, preparation and isolation of uncommon primary sulfinamidines, the aza‐analogues of sulfinamides, is highly desirable. Here we report a multistep continuous flow synthe...

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Detalles Bibliográficos
Autores principales: Andresini, Michael, Carret, Sébastien, Degennaro, Leonardo, Ciriaco, Fulvio, Poisson, Jean‐François, Luisi, Renzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804385/
https://www.ncbi.nlm.nih.gov/pubmed/35861934
http://dx.doi.org/10.1002/chem.202202066