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Implementation of NUDT15 Genotyping to Prevent Azathioprine‐Induced Leukopenia for Patients With Autoimmune Disorders in Chinese Population

Azathioprine (AZA) is commonly used for many autoimmune disorders; however, the limitation of its clinical use is due to potential toxicities, including severe leukopenia. Recent studies have identified genetic NUDT15 variants strongly associated with AZA‐induced leukopenia in Asian patients. This s...

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Detalles Bibliográficos
Autores principales: Wang, Chuang‐Wei, Chi, Min‐Hui, Tsai, Tsen‐Fang, Yu, Kuang‐Hui, Kao, Hsiao‐Wen, Chen, Hsiang‐Cheng, Chen, Chun‐Bing, Lu, Chun‐Wei, Chen, Wei‐Ti, Chang, Ya‐Ching, Chang, Chih‐Jung, Chang, Yun‐Ting, Jan Wu, Yeong‐Jian, Chang, Chee‐Jen, Huang, Yu Huei, Ng, Chau‐Yee, Huang, Po‐Wei, Lin, Yu‐Jr, Hui, Rosaline Chung‐Yee, Chung, Wen‐Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804440/
https://www.ncbi.nlm.nih.gov/pubmed/35869597
http://dx.doi.org/10.1002/cpt.2716