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A Formylglycine‐Peptide for the Site‐Directed Identification of Phosphotyrosine‐Mimetic Fragments

Discovery of protein‐binding fragments for precisely defined binding sites is an unmet challenge to date. Herein, formylglycine is investigated as a molecular probe for the sensitive detection of fragments binding to a spatially defined protein site . Formylglycine peptide 3 was derived from a phosp...

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Detalles Bibliográficos
Autores principales: Tiemann, Markus, Nawrotzky, Eric, Schmieder, Peter, Wehrhan, Leon, Bergemann, Silke, Martos, Vera, Song, Wei, Arkona, Christoph, Keller, Bettina G., Rademann, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804470/
https://www.ncbi.nlm.nih.gov/pubmed/35781901
http://dx.doi.org/10.1002/chem.202201282