Synthesis of α‐Aryl Acrylamides via Lewis‐Base‐Mediated Aryl/Hydrogen Exchange

Herein we report a method for the synthesis of α‐aryl acrylamides leveraging polar S‐to‐C aryl migrations induced by a Lewis basic organocatalyst. In contrast to previously reported radical aryl migrations of sulfonyl acrylimides, this polar process enables subsequent elimination, ultimately leading...

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Detalles Bibliográficos
Autores principales: Lemmerer, Miran, Zhang, Haoqi, Fernandes, Anthony J., Fischer, Tobias, Mießkes, Marianne, Xiao, Yi, Maulide, Nuno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804524/
https://www.ncbi.nlm.nih.gov/pubmed/35881564
http://dx.doi.org/10.1002/anie.202207475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804524/
https://www.ncbi.nlm.nih.gov/pubmed/35881564
http://dx.doi.org/10.1002/anie.202207475

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