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Higher susceptibility to 6 Hz corneal kindling and lower responsiveness to antiseizure drugs in mouse models of Alzheimer's disease

OBJECTIVE: Epileptic spikes and seizures seem present early in the disease process of Alzheimer's disease (AD). However, it is unclear how soluble and insoluble amyloid beta (Aβ) and tau proteins affect seizure development in vivo. We aim to contribute to this field by assessing the vulnerabili...

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Detalles Bibliográficos
Autores principales: Vande Vyver, Maxime, Barker‐Haliski, Melissa, Aourz, Najat, Nagels, Guy, Bjerke, Maria, Engelborghs, Sebastiaan, De Bundel, Dimitri, Smolders, Ilse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804582/
https://www.ncbi.nlm.nih.gov/pubmed/35775150
http://dx.doi.org/10.1111/epi.17355