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The mitotic regulator polo‐like kinase 1 as a potential therapeutic target for c‐Myc‐overexpressing canine osteosarcomas

Osteosarcoma is the most common primary malignant bone tumour in dogs, characterized by a locally aggressive and highly metastatic behaviour. Despite the current standards of care, most dogs succumb to the disease, indicating the need for novel treatment strategies. Polo‐like kinase 1 (PLK1) is dysr...

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Detalles Bibliográficos
Autores principales: Gola, Cecilia, Licenziato, Luca, Accornero, Paolo, Iussich, Selina, Morello, Emanuela, Buracco, Paolo, Modesto, Paola, Aresu, Luca, De Maria, Raffaella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804590/
https://www.ncbi.nlm.nih.gov/pubmed/36054794
http://dx.doi.org/10.1111/vco.12854