A low‐cost, sensitive and specific PCR‐based tool for rapid clinical detection of HLA‐B*35 alleles associated with delayed drug hypersensitivity reactions

HLA (HLA) alleles are risk factors for CD8+ T‐cell‐mediated drug hypersensitivity reactions. However, as most HLA associations are incompletely predictive and/or involve risk alleles at low frequency, costly sequence‐based typing can elude an economically productive cost: benefit ratio for clinical...

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Detalles Bibliográficos
Autores principales: Li, Yueran, Deshpande, Pooja, Chopra, Abha, Choo, Linda, Gibson, Andrew, Phillips, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804599/
https://www.ncbi.nlm.nih.gov/pubmed/35968750
http://dx.doi.org/10.1111/tan.14767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804599/
https://www.ncbi.nlm.nih.gov/pubmed/35968750
http://dx.doi.org/10.1111/tan.14767

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