Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations

Clinical studies in healthy volunteers challenged with lipopolysaccharide (LPS), a constituent of the cell wall of Gram‐negative bacteria, represent a key model to characterize the Toll‐like receptor 4 (TLR4)‐mediated inflammatory response. Here, we developed a mathematical modelling framework to qu...

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Detalles Bibliográficos
Autores principales: Liu, Feiyan, Aulin, Linda B. S., Guo, Tingjie, Krekels, Elke H. J., Moerland, Matthijs, van der Graaf, Piet H., van Hasselt, Johan G. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804664/
https://www.ncbi.nlm.nih.gov/pubmed/35921300
http://dx.doi.org/10.1111/bcp.15476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804664/
https://www.ncbi.nlm.nih.gov/pubmed/35921300
http://dx.doi.org/10.1111/bcp.15476

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