Cargando…

Modelling inflammatory biomarker dynamics in a human lipopolysaccharide (LPS) challenge study using delay differential equations

Clinical studies in healthy volunteers challenged with lipopolysaccharide (LPS), a constituent of the cell wall of Gram‐negative bacteria, represent a key model to characterize the Toll‐like receptor 4 (TLR4)‐mediated inflammatory response. Here, we developed a mathematical modelling framework to qu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Feiyan, Aulin, Linda B. S., Guo, Tingjie, Krekels, Elke H. J., Moerland, Matthijs, van der Graaf, Piet H., van Hasselt, Johan G. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804664/ https://www.ncbi.nlm.nih.gov/pubmed/35921300 http://dx.doi.org/10.1111/bcp.15476

Ejemplares similares

A system pharmacology Boolean network model for the TLR4-mediated inflammatory response in early sepsis
por: Liu, Feiyan, et al.
Publicado: (2022)

Unraveling the Effects of Acute Inflammation on Pharmacokinetics: A Model-Based Analysis Focusing on Renal Glomerular Filtration Rate and Cytochrome P450 3A4-Mediated Metabolism
por: Liu, Feiyan, et al.
Publicado: (2023)

Characterizing the kinetics of presepsin and associated inflammatory biomarkers in human endotoxemia
por: Aulin, Linda B. S., et al.
Publicado: (2022)

Evaluation of a Cardiovascular Systems Model for Design and Analysis of Hemodynamic Safety Studies
por: Fu, Yu, et al.
Publicado: (2023)

Design principles of collateral sensitivity-based dosing strategies
por: Aulin, Linda B. S., et al.
Publicado: (2021)

Predictions of Bedaquiline and Pretomanid Target Attainment in Lung Lesions of Tuberculosis Patients using Translational Minimal Physiologically Based Pharmacokinetic Modeling
por: Mehta, Krina, et al.
Publicado: (2023)

Biomarker‐Guided Individualization of Antibiotic Therapy
por: Aulin, Linda B.S., et al.
Publicado: (2021)

Validation of a Model Predicting Anti-infective Lung Penetration in the Epithelial Lining Fluid of Humans
por: Aulin, Linda B. S., et al.
Publicado: (2018)

Physiologically Based Modelling Framework for Prediction of Pulmonary Pharmacokinetics of Antimicrobial Target Site Concentrations
por: Aulin, Linda B. S., et al.
Publicado: (2022)

Children Are Not Small Adults, but Can We Treat Them As Such?
por: Krekels, Elke H.J., et al.
Publicado: (2019)

Systematic Evaluation of the Descriptive and Predictive Performance of Paediatric Morphine Population Models
por: Krekels, Elke H. J., et al.
Publicado: (2010)

Outside‐In Systems Pharmacology Combines Innovative Computational Methods With High‐Throughput Whole Vertebrate Studies
por: Schulthess, Pascal, et al.
Publicado: (2018)

Impact of post-hatching maturation on the pharmacokinetics of paracetamol in zebrafish larvae
por: van Wijk, Rob C., et al.
Publicado: (2019)

Quantification of Natural Growth of Two Strains of Mycobacterium Marinum for Translational Antituberculosis Drug Development
por: Van Wijk, Rob C., et al.
Publicado: (2020)

Integration of pharmacometabolomics with pharmacokinetics and pharmacodynamics: towards personalized drug therapy
por: Kantae, Vasudev, et al.
Publicado: (2016)

T Cell Stimulation In Vivo by Lipopolysaccharide (LPS)
por: Tough, David F., et al.
Publicado: (1997)

Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14
Publicado: (1994)

Lipopolysaccharide (LPS) segmental lung challenge in nonhuman primates – a model of airway inflammation
por: Schlerman, Franklin J, et al.
Publicado: (2013)

Lipopolysaccharide (LPS) stimulation of fungal secondary metabolism
por: Khalil, Zeinab G., et al.
Publicado: (2014)

Intradermal lipopolysaccharide challenge as an acute in vivo inflammatory model in healthy volunteers
por: Buters, Thomas P., et al.
Publicado: (2021)

Effects of L-proline on the Growth Performance, and Blood Parameters in Weaned Lipopolysaccharide (LPS)-challenged Pigs
por: Kang, Ping, et al.
Publicado: (2014)

Pharmacokinetic Modeling of Paracetamol Uptake and Clearance in Zebrafish Larvae: Expanding the Allometric Scale in Vertebrates with Five Orders of Magnitude
por: Kantae, Vasudev, et al.
Publicado: (2016)

Potential Influence of Endothelial Adsorption on the Delayed Time to Maximum Concentration of Biopharmaceuticals
por: Reijers, Joannes A. A., et al.
Publicado: (2017)

Allele-specific collateral and fitness effects determine the dynamics of fluoroquinolone resistance evolution
por: Liakopoulos, Apostolos, et al.
Publicado: (2022)

Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS
Publicado: (1994)

Attenuation of lipopolysaccharide (LPS)-induced cytotoxicity by tocopherols and tocotrienols()
por: Nishio, Keiko, et al.
Publicado: (2013)

Lipopolysaccharide (LPS)-Induced Autophagy Is Responsible for Enhanced Osteoclastogenesis
por: Sul, Ok-Joo, et al.
Publicado: (2017)

Effects of Sihuang Zhili Granules on the Diarrhea Symptoms, Immunity, and Antioxidant Capacity of Poultry Challenged with Lipopolysaccharide (LPS)
por: Wang, Shaolong, et al.
Publicado: (2023)

Mice Genetically Hyporesponsive to Lipopolysaccharide (LPS) Exhibit a Defect in Endocytic Uptake of LPS and Ceramide
por: Thiéblemont, Nathalie, et al.
Publicado: (1997)

Book Review: Pharmacokinetic and Pharmacodynamic Data Analysis ‐ Concepts and Applications, 5th Edition, by Johan Gabrielsson and Daniel Weiner Apotekarsocieteten, 2016 1,040 pp, hardcover ISBN: 9789198299106
por: Krekels, Elke H.J.
Publicado: (2016)

The Duffy antigen receptor for chemokines (DARC) and acute renal failure (ARF) during lipopolysaccharide (LPS)-induced systemic inflammation
por: Singbartl, K, et al.
Publicado: (2004)

Lipopolysaccharide (LPS) binding protein opsonizes LPS-bearing particles for recognition by a novel receptor on macrophages
Publicado: (1989)

Geranylgeranylacetone Ameliorates Inflammatory Response to Lipopolysaccharide (LPS) in Murine Macrophages: Inhibition of LPS Binding to The Cell Surface
por: Mochida, Shinsuke, et al.
Publicado: (2007)

Anti‐tuberculosis effect of isoniazid scales accurately from zebrafish to humans
por: van Wijk, Rob C., et al.
Publicado: (2020)

Bartonella quintana lipopolysaccharide (LPS): structure and characteristics of a potent TLR4 antagonist for in-vitro and in-vivo applications
por: Malgorzata-Miller, Gosia, et al.
Publicado: (2016)

Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments
por: Calvier, Elisa A. M., et al.
Publicado: (2018)

Granulocyte Colony Stimulating Factor Induces Lipopolysaccharide (LPS) Sensitization via Upregulation of LPS Binding Protein in Rat
por: Fang, Haoshu, et al.
Publicado: (2013)

Minocycline attenuates lipopolysaccharide (LPS)-induced neuroinflammation, sickness behavior, and anhedonia
por: Henry, Christopher J, et al.
Publicado: (2008)

Upregulation of prolylcarboxypeptidase (PRCP) in lipopolysaccharide (LPS) treated endothelium promotes inflammation
por: Ngo, My-Linh, et al.
Publicado: (2009)

Oenothein B Suppresses Lipopolysaccharide (LPS)-Induced Inflammation in the Mouse Brain
por: Okuyama, Satoshi, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_cu0r3vdgvmk8sremb58aln3k2r