Identification of a Novel Pseudo‐Natural Product Type IV IDO1 Inhibitor Chemotype

Natural product (NP)‐inspired design principles provide invaluable guidance for bioactive compound discovery. Pseudo‐natural products (PNPs) are de novo combinations of NP fragments to target biologically relevant chemical space not covered by NPs. We describe the design and synthesis of apoxidoles,...

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Detalles Bibliográficos
Autores principales: Davies, Caitlin, Dötsch, Lara, Ciulla, Maria Gessica, Hennes, Elisabeth, Yoshida, Kei, Gasper, Raphael, Scheel, Rebecca, Sievers, Sonja, Strohmann, Carsten, Kumar, Kamal, Ziegler, Slava, Waldmann, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804781/
https://www.ncbi.nlm.nih.gov/pubmed/35959923
http://dx.doi.org/10.1002/anie.202209374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804781/
https://www.ncbi.nlm.nih.gov/pubmed/35959923
http://dx.doi.org/10.1002/anie.202209374

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