Investigating the prediction of CpG methylation levels from SNP genotype data to help elucidate relationships between methylation, gene expression and complex traits

As popularised by PrediXcan (and related methods), transcriptome‐wide association studies (TWAS), in which gene expression is imputed from single‐nucleotide polymorphism (SNP) genotypes and tested for association with a phenotype, are a popular approach for investigating the role of gene expression...

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Detalles Bibliográficos
Autores principales: Fryett, James J., Morris, Andrew P., Cordell, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804820/
https://www.ncbi.nlm.nih.gov/pubmed/35930604
http://dx.doi.org/10.1002/gepi.22496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804820/
https://www.ncbi.nlm.nih.gov/pubmed/35930604
http://dx.doi.org/10.1002/gepi.22496

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