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Transcriptional regulation of ergosterol biosynthesis genes in response to iron deficiency

Iron participates as an essential cofactor in the biosynthesis of critical cellular components, including DNA, proteins and lipids. The ergosterol biosynthetic pathway, which is an important target of antifungal treatments, depends on iron in four enzymatic steps. Our results in the model yeast Sacc...

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Detalles Bibliográficos
Autores principales: Jordá, Tania, Barba‐Aliaga, Marina, Rozès, Nicolas, Alepuz, Paula, Martínez‐Pastor, María Teresa, Puig, Sergi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804849/
https://www.ncbi.nlm.nih.gov/pubmed/36382795
http://dx.doi.org/10.1111/1462-2920.16157