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Transcriptional regulation of ergosterol biosynthesis genes in response to iron deficiency
Iron participates as an essential cofactor in the biosynthesis of critical cellular components, including DNA, proteins and lipids. The ergosterol biosynthetic pathway, which is an important target of antifungal treatments, depends on iron in four enzymatic steps. Our results in the model yeast Sacc...
Autores principales: | Jordá, Tania, Barba‐Aliaga, Marina, Rozès, Nicolas, Alepuz, Paula, Martínez‐Pastor, María Teresa, Puig, Sergi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804849/ https://www.ncbi.nlm.nih.gov/pubmed/36382795 http://dx.doi.org/10.1111/1462-2920.16157 |
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