Novel Poxin Stable cGAMP‐Derivatives Are Remarkable STING Agonists

2′,3′‐cGAMP is a cyclic A‐ and G‐containing dinucleotide second messenger, which is formed upon cellular recognition of foreign cytosolic DNA as part of the innate immune response. The molecule binds to the adaptor protein STING, which induces an immune response characterized by the production of ty...

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Detalles Bibliográficos
Autores principales: Stazzoni, Samuele, Böhmer, Daniel F. R., Hernichel, Fabian, Özdemir, Dilara, Pappa, Aikaterini, Drexler, David, Bauernfried, Stefan, Witte, Gregor, Wagner, Mirko, Veth, Simon, Hopfner, Karl‐Peter, Hornung, Veit, König, Lars M., Carell, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804856/
https://www.ncbi.nlm.nih.gov/pubmed/35876840
http://dx.doi.org/10.1002/anie.202207175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804856/
https://www.ncbi.nlm.nih.gov/pubmed/35876840
http://dx.doi.org/10.1002/anie.202207175

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