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Effects of cell seeding technique and cell density on BMP‐2 production in transduced human mesenchymal stem cells

Small animal models have demonstrated the efficacy of ex vivo regional gene therapy using scaffolds loaded with BMP‐2‐expressing mesenchymal stem cells (MSCs). Prior to clinical translation, optimization of seeding techniques of the transduced cells will be important to minimize time and resource ex...

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Detalles Bibliográficos
Autores principales: Collon, Kevin, Bell, Jennifer A., Chang, Stephanie W., Gallo, Matthew C., Sugiyama, Osamu, Marks, Carolyn, Lieberman, Jay R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804863/
https://www.ncbi.nlm.nih.gov/pubmed/35950648
http://dx.doi.org/10.1002/jbm.a.37430