Suppression of myeloid PFKFB3‐driven glycolysis protects mice from choroidal neovascularization

BACKGROUND AND PURPOSE: Pathological angiogenesis is a major cause of irreversible blindness in individuals with neovascular age‐related macular degeneration (nAMD). Macrophages and microglia (MΦ) contribute to aberrant ocular angiogenesis. However, the role of glucose metabolism of MΦ in nAMD is st...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Zhiping, Mao, Xiaoxiao, Yang, Qiuhua, Zhang, Xiaoyu, Xu, Jiean, Ma, Qian, Zhou, Yaqi, Da, Qingen, Cai, Yongfeng, Sopeyin, Anu, Dong, Zheng, Hong, Mei, Caldwell, Ruth B., Sodhi, Akrit, Huo, Yuqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804921/
https://www.ncbi.nlm.nih.gov/pubmed/35830274
http://dx.doi.org/10.1111/bph.15925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804921/
https://www.ncbi.nlm.nih.gov/pubmed/35830274
http://dx.doi.org/10.1111/bph.15925

Ejemplares similares