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Suppression of myeloid PFKFB3‐driven glycolysis protects mice from choroidal neovascularization
BACKGROUND AND PURPOSE: Pathological angiogenesis is a major cause of irreversible blindness in individuals with neovascular age‐related macular degeneration (nAMD). Macrophages and microglia (MΦ) contribute to aberrant ocular angiogenesis. However, the role of glucose metabolism of MΦ in nAMD is st...
Autores principales: | Liu, Zhiping, Mao, Xiaoxiao, Yang, Qiuhua, Zhang, Xiaoyu, Xu, Jiean, Ma, Qian, Zhou, Yaqi, Da, Qingen, Cai, Yongfeng, Sopeyin, Anu, Dong, Zheng, Hong, Mei, Caldwell, Ruth B., Sodhi, Akrit, Huo, Yuqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804921/ https://www.ncbi.nlm.nih.gov/pubmed/35830274 http://dx.doi.org/10.1111/bph.15925 |
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