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Phase Separation of Heterogeneous Nuclear Ribonucleoprotein A1 upon Specific RNA‐Binding Observed by Magnetic Resonance

Interaction of heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) with specific single‐stranded RNA and its relation to liquid‐liquid phase separation (LLPS) were studied in vitro by magnetic resonance based on site‐directed spin labelling. An ensemble model of dispersed hnRNP A1 in the absence o...

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Detalles Bibliográficos
Autores principales: Ritsch, Irina, Lehmann, Elisabeth, Emmanouilidis, Leonidas, Yulikov, Maxim, Allain, Frédéric, Jeschke, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804974/
https://www.ncbi.nlm.nih.gov/pubmed/35866309
http://dx.doi.org/10.1002/anie.202204311