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Analysis of fibrinogen concentrate pharmacokinetics and dosing for bleeds and surgery in adults, adolescents, and children with congenital afibrinogenaemia and hypofibrinogenaemia

INTRODUCTION: Congenital afibrinogenaemia and hypofibrinogenaemia are rare coagulation disorders where clotting is impaired due to a lack of fibrinogen. Consequent bleeding episodes (BEs) are treated using human fibrinogen concentrate (HFC). AIM: This post‐hoc analysis compared HFC pharmacokinetics...

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Detalles Bibliográficos
Autores principales: Djambas Khayat, Claudia, Lohade, Sunil D., Zekavat, Omid R., Kruzhkova, Irina, Solomon, Cristina, Knaub, Sigurd, Peyvandi, Flora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804975/
https://www.ncbi.nlm.nih.gov/pubmed/35925493
http://dx.doi.org/10.1111/hae.14619