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Diastereoselective, Catalytic Access to Cross‐Aldol Products Directly from Esters and Lactones

High oxidation‐state carbonyl coupling partners including esters and lactones were reacted with enones to give aldol‐type products directly using two‐fold organoborane catalysis. This new retrosynthetic disconnection to aldol‐type products is compatible with enolisable coupling partners, without sel...

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Detalles Bibliográficos
Autores principales: Moreno González, Adrián, Nicholson, Kieran, Llopis, Natalia, Nichol, Gary S., Langer, Thomas, Baeza, Alejandro, Thomas, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9804986/
https://www.ncbi.nlm.nih.gov/pubmed/35916601
http://dx.doi.org/10.1002/anie.202209584