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Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells

BACKGROUND: Attenuated Oxaliplatin efficacy is a challenge in treating colorectal cancer (CRC) patients, contributory to the failure in chemotherapy and the risks in relapse and metastasis. However, the mechanism of Oxaliplatin de-efficacy during CRC treatment has not been completely elucidated. MET...

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Detalles Bibliográficos
Autores principales: Liu, Xiaohui, Wu, Bo, Chen, Hong, Sun, Haimei, Guo, Xiaoxia, Sun, Tingyi, Zhou, Deshan, Yang, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805014/
https://www.ncbi.nlm.nih.gov/pubmed/36585626
http://dx.doi.org/10.1186/s12885-022-10415-8