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Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
BACKGROUND: Attenuated Oxaliplatin efficacy is a challenge in treating colorectal cancer (CRC) patients, contributory to the failure in chemotherapy and the risks in relapse and metastasis. However, the mechanism of Oxaliplatin de-efficacy during CRC treatment has not been completely elucidated. MET...
Autores principales: | Liu, Xiaohui, Wu, Bo, Chen, Hong, Sun, Haimei, Guo, Xiaoxia, Sun, Tingyi, Zhou, Deshan, Yang, Shu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805014/ https://www.ncbi.nlm.nih.gov/pubmed/36585626 http://dx.doi.org/10.1186/s12885-022-10415-8 |
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