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Molecular mechanisms involved in the IL-6-mediated upregulation of indoleamine 2,3-dioxygenase 1 (IDO1) expression in the chorionic villi and decidua of women in early pregnancy

BACKGROUND: IL-6 induces the upregulation of indoleamine 2,3-dioxygenase (IDO1) at the maternal-foetal interface, but the regulation mechanisms of IDO1 by IL-6 at this interface have not been fully understood. METHODS: Western blotting, qRT–PCR and/or immunohistochemistry were employed to measure th...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Zhao, Shuyun, Chen, Xiaojuan, Xiao, Ziwen, Wen, Xinghui, Zhong, Xingming, Li, Shixiang, Cheng, Hui, Huang, Guanyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805015/
https://www.ncbi.nlm.nih.gov/pubmed/36587196
http://dx.doi.org/10.1186/s12884-022-05307-5