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A paradigm shift in pharmacogenomics: From candidate polymorphisms to comprehensive sequencing
Genetic factors have long been recognized as important determinants of interindividual variability in drug efficacy and toxicity. However, despite the increasing number of established gene–drug associations, candidate polymorphisms can only explain a fraction of the genetically encoded functional va...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805052/ https://www.ncbi.nlm.nih.gov/pubmed/35971800 http://dx.doi.org/10.1111/bcpt.13779 |