The integrin ligand SVEP1 regulates GPCR‐mediated vasoconstriction via integrins α9β1 and α4β1

BACKGROUND AND PURPOSE: Vascular tone is regulated by the relative contractile state of vascular smooth muscle cells (VSMCs). Several integrins directly modulate VSMC contraction by regulating calcium influx through L‐type voltage‐gated Ca(2+) channels (VGCCs). Genetic variants in ITGA9, which encod...

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Detalles Bibliográficos
Autores principales: Morris, Gavin E., Denniff, Matthew J., Karamanavi, Elisavet, Andrews, Sarah A., Kostogrys, Renata B., Bountziouka, Vasiliki, Ghaderi‐Najafabadi, Maryam, Shamkhi, Noor, McConnell, George, Kaiser, Michael A., Carleton, Laura, Schofield, Christine, Kessler, Thorsten, Rainbow, Richard D., Samani, Nilesh J., Webb, Thomas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805129/
https://www.ncbi.nlm.nih.gov/pubmed/35802072
http://dx.doi.org/10.1111/bph.15921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805129/
https://www.ncbi.nlm.nih.gov/pubmed/35802072
http://dx.doi.org/10.1111/bph.15921

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